Guidelines for Diagnosis of Alzheimer's Disease

A) Probable Alzheimer's

• Gradual cognitive decline in memory AND one other function
• Age 50-100
• Normal level of consciousness
• Impaired function
• Associated personality or behavioral changes
• Absence of other systemic disorder as etiology
• MMSE < 21-25 (by education level)

B) Possible Alzheimer's- Same as above but other potential etiologic condition is present. (e.g. Parkinson's, depression)

C) Definite Alzheimer's- Clinical symptoms and Brain Tissue